Which agents are used to perform a gallbladder ejection fraction?

Sincalide and Disofenin are the recommended agents for performing a gallbladder ejection fraction study. Sincalide is a synthetic analog of cholecystokinin, a hormone that stimulates gallbladder contraction and bile release. By administering Sincalide, the gallbladder can be effectively stimulated to gauge its ejection fraction, which is a critical measure of gallbladder function.

Disofenin, on the other hand, is a radiopharmaceutical used for imaging the hepatobiliary system. When combined with Sincalide, it allows for the quantification of the gallbladder's ability to eject bile, thus providing valuable information about the organ’s functional state during the examination.

The combination of these two agents makes them particularly effective for the evaluation of gallbladder function, which is essential for diagnosing various biliary tract disorders. This synergy ensures that the assessment of gallbladder ejection fraction is both accurate and reliable.