If a new generator is eluted several times and the amount of Al in the eluate exceeds the USP limit, what should the technologist do?

When the amount of aluminum (Al) in the eluate exceeds the United States Pharmacopeia (USP) limit, it indicates a potential issue with the generator that could affect the quality and safety of the radiopharmaceuticals being produced. In such a situation, contacting the generator manufacturer is the appropriate course of action.

The manufacturer has the expertise and resources to assess the problem, and they can provide guidance or solutions based on the specific circumstances surrounding the generator. This step is crucial not only for regulatory compliance but also to ensure patient safety and the efficacy of the nuclear medicine procedures.

Continuing to use the generator when it is producing eluate with excessive aluminum levels could lead to compromised patient safety and could also result in non-compliance with regulatory standards. Diluting the eluate does not address the underlying problem of contamination and may not ensure that the levels remain within acceptable limits. Discarding the generator might seem like a straightforward solution, but it is more prudent to consult with the manufacturer first to explore if the generator can be serviced or stabilized.